Isu tiri vamwe vevatungamirin-methylbenzamide vatengesiuye vagadziri muchina, kana iwe uchida kuwanan-methylbenzamide fekitari, inzwa wakasununguka kutibata uye utidonhedze email.
1. ChiiN-Methylbenzamide?
N-methylbenzamide inoshanda phosphodiesterase 10A (pde10a) inhibitor.N-methylbenzamide ine anticancer chiitiko.PDE10A ichangobva kuzivikanwa phosphodiesterase ine inoshamisa yenzvimbo sezvo mapuroteni ari kuwanda muuropi chete.Kubva pane iyi yakasarudzika yenzvimbo, tsvagiridzo yakanangana zvakanyanya nekushandisa PDE10A modulators seyazvino nzira yekurapa yekusashanda mu basal ganglia wedunhu kusanganisira chirwere cheParkinson, chirwere chaHuntington, schizophrenia, kupindwa muropa uye obsessive compulsive disorder.Mishonga yemakemikari kuedza yakaratidza N-methyl-N- [4- (quinolin-2-ylmethoxy) -phenyl] -isonicotinamide se nanomolar PDE10A inhibitor.Imwe inotevera Lead-optimization chirongwa chakaratidza anologous N-methylanilides uye yavo inoenderana N-methylbenzamide seyakasimba PDE10A inhibitors, panguva imwe chete mamwe anonakidza uye asingatarisirwe anosunga modhi akaonekwa.
Kunyungudika 76-78 ° C
Kubikira nzvimbo 167 ° C
Density 1.1031
Refractive index 1.5589
Kuchengetedza mamiriro akavharwa akaoma, kamuri tembiricha
Solubility ethanol: soluble 50mg / ml, mvura solubility: Insoluble mumvura
CAS:613-93-4
Chitarisiko: White Crystalline
2. Main application
Inhibitor, anticancer, organic synthesis yepakati, marabhoritari makemikari
3.Kuchengeta uye Kurongedza
3.Matanho ekutanga ekubatsira
Kubata Kweziso: Shamba nekukasira nemvura yakawanda, zvakare pasi pemaziso, kweanenge maminetsi gumi nemashanu.Wana kurapwa.
Kubata Paganda: Geza nekukasika nesipo nemvura yakawanda uchibvisa mbatya neshangu zvine utachiona.
Inhalation: Bvisa kubva pakuratidzwa, rara pasi.Bvisa kumhepo itsva.Kana usingafeme, ipa artificial kufema.
Kudya: Geza mukanwa nemvura.Wana kurapwa.
Chinonyanya kukosha zviratidzo nemhedzisiro: Hapana ruzivo rwuripo.
Kuzvidzivirira kweMubatsiri Wokutanga: Hapana matanho anokosha anodiwa.
Notes kuna Chiremba: Rapa zviratidzo.
4. Mashoko ekufambisa
Kutakura Mugwagwa Nenjanji: Haina Kudzorwa
IMDG/IMO : Haina kudzorwa
IATA : Haina kudzorwa
Special Chengetedzo kune Mushandisi: Hapana akakosha ekuchengetedza anodiwa
5. HTML5 spectrum
Hebei Guanlang Biotechnology Co., Ltd. ndeyeGuanlang Group, iyo yakavambwa muna 2007, iri muguta reShijiazhuang rinova guta guru reHebei Province uye hub sector pakati peBeijing Tianjin neHebei uye ine mukana wekufambisa kuri nyore.Kambani yedu ibhizimusi remazuva ano repamusoro-soro remakemikari rine Tsvagiridzo & Kuvandudza, kugadzira uye kutengesa. Isu tine fekitori yedu uye lab, zvakare tinopa yakagadziridzwa sevhisi yekubatanidza kune vatengi vedu.
