Kubva mugore ra2007, isu tiri vamwe vekutungamiraorlistat powdermutengesi muchina
Orlistat (CAS NO.96829-58-2) mushonga wakagadzirirwa kurapa kufuta.Inonyanya kushandiswa kudzivirira kutorwa kwemafuta kubva mukudya kwevanhu, nokudaro kuderedza caloric kudya.Kunze kwezvo, inotarisirwa kushandiswa pamwe chete nachiremba-anotarisirwa kuderedzwa-calorie kudya.
| Item | Zvinodiwa | Test Results |
| Chitarisiko | uchienda kure-uchiri upfu | Upfu chena |
| Identification | HPLC kuchengetedza nguva | Conforms |
| Melting Point | 42 ºC -45°C | 42°C-44°C |
| Specific optical rotation | -31.0°~-41.0° | -36.0° |
| Kuchena neHPLC | kwete pasi pe98.0% | 98.5% |
| Kusachena zvachose | hapana kupfuura 2.0% | 1.6% |
| Max Individual kusachena | hapana kupfuura 0.5% | 0.3% |
| Zvemumvura%(K&F) | hapana kupfuura 0.5% | 0.1% |
| Residual solvents | EtOH hapana kupfuura 0.5% | ND |
| EtAC hapana kupfuura 0.5% | ND | |
| n-Heptane hapana kupfuura 0.5% | isingasviki 0.1% | |
| Residue pamoto | isingasviki 0.2% | 0.10% |
| Heavy metals sePb | hapana kupfuura 20ppm | isingasviki 20ppm |
| Kuongorora (HPLC) | kwete pasi pe98.0% | 99.60% |
| Mhedziso | Zvinoita Zvinodiwa | |
Orlistat inzira itsva inozivikanwa pasi rese yekurasikirwa uremu mushonga.Zita rayo rekutengeserana rinonzi Sainike uye rakatanga kutengeswa muNew Zealand muna 1998. Orlistat inguva yakareba uye inoshanda zvakanyanya yegastrointestinal lipase inhibitor, uye haigadziriswi mumvura, inonyunguduka mu chloroform, uye inonyungudika nyore nyore mu ethanol.
Orlistat inogona kushandiswa kuchipatara kurapa kufutisa.Kazhinji, chiyero che 120mg chinotorwa katatu pazuva mukati meawa imwe yekudya.Kurasikirwa uremu kunotanga kuitika mushure memavhiki maviri ekushandiswa.Inogona kushandiswa nguva dzose kwemwedzi 6-12, uye migumisiro yayo icharega kuwedzera mushure mezuva nezuva dosi inodarika 400mg.Mushonga uyu wakakodzera kushandiswa pamwe chete nekudya kwakaderera-koriori nevanhu vakafutisa uye vakafutisa, uye inogona kushandiswa sekurapa kwenguva refu kune varwere vakasangana nehuremu hunoenderana nenjodzi.Orlistat ine huremu hwehuremu hwehuremu hurefu hunoderedza uye hunochengetedza huremu uye hunodzivirira kubva pakudzoka.Kushandisa Orlistat kunogona kuderedza zviitiko zvehuremu-hunoenderana nenjodzi uye zvirwere, zvinosanganisira hypercholesterolemia, Type-2 chirwere cheshuga, kukanganiswa kweglucose kushivirira, hyperinsulinemia, uye hypertension, uye inogona kuderedza mafuta ari munhengo.Orlistat inogadzirisawo mazinga eropa: inogona kuderedza serum triglycerides (TG) uye yakaderera density lipoprotein cholesterol (LDL-C), uye inogona kuwedzera chiyero chepamusoro density lipoproteins kune yakaderera density lipoproteins muvarwere vakafuta.
Hebei Guanlang Biotechnology Co., Ltd. ndeyeGuanlang Group, iyo yakavambwa muna 2007, iri muguta reShijiazhuang rinova guta guru reHebei Province uye hub sector pakati peBeijing Tianjin neHebei uye ine mukana wekufambisa kuri nyore.Kambani yedu ibhizimusi remazuva ano repamusoro-soro remakemikari rine Tsvagiridzo & Kuvandudza, kugadzira uye kutengesa. Isu tine fekitori yedu uye lab, zvakare tinopa yakagadziridzwa sevhisi yekubatanidza kune vatengi vedu.
